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Qualifications:
PhD in Human Physiology (UKZN), Master of Medical Sciences (UKZN), B Medical Sciences (Honours) (UKZN), B Medical Sciences (UKZN)

Professional Affiliations:

Physiological Society of Southern Africa

Southern African Neuroscience Society

Teaching:

Pharmacy Anatomy and Physiology, Pathophysiology and Pathology

Research Interests:

My primary research seeks to screen for novel synthetic or natural compounds as potential agents for diabetes mellitus using quick screening tools invitro as well as animal models in vivo.

Recent Publications:

1. Bonisiwe Mbatha, Andile Khathi, Ntethelelo Sibiya, Irvin Booysen, Patrick Mangundu, Phikelelani Ngubane (Accepted in 2020). Antihyperglycaemic effect of a dioxidovanadium complex avert kidney dysfunction in streptozotocin-induced diabetic rats male Sprague-dawly rats. Canadian Journal of Physiology and Pharmacology
2. Angezwa Siboto, Bongiwe Khumalo, Akinjide Akinnuga, Ntethelelo Sibiya, Irvin Booysen, Phikelelani Ngubane, Andile Khathi (2020). The effect of a [3+1] oxo-free rhenium (V) compound with uracil derived ligands on selected parameters of glucose homeostasis in diet-induced diabetic rats. Obesity Medicine
3. Akinjide Moses Akinnuga, Bongiwe Khumalo, Angezwa Siboto, Ntethelelo Sibiya, Phikelelani Ngubane, Andile Khathi (2020). Ameliorative effects of bredemolic acid on markers associated with renal dysfunction in a diet induced pre-diabetic model. Oxidative medicine and Cellular longevity
4. Akinjide Moses Akinnuga, Bongiwe Khumalo, Angezwa Siboto, Ntethelelo Sibiya, Phikelelani Ngubane, Andile Khathi (2020). Bredemolic Acid Improves Cardiovascular Function and Attenuates Endothelial Dysfunction in Diet-Induced Prediabetes: Effects on Selected Markers. Cardiovascular Therapeutics https://doi.org/10.1155/2020/1936406
5. Akinjide Moses Akinnuga, Bongiwe Khumalo, Angezwa Siboto, Ntethelelo Sibiya, Phikelelani Ngubane, Andile Khathi (2020). Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model. Canadian Journal of Gastroenterology and Hepatology https://doi.org/10.1155/2020/2475301
6. Akinjide Moses Akinnuga, Bongiwe Khumalo, Angezwa Siboto, Ntethelelo Sibiya, Phikelelani Ngubane, Andile Khathi (2019). Evaluation of the effects of bredemolic acid on selected markers of glucose homeostasis in diet-induced prediabetic rats. Journal of Physiology and Biochemistry https://doi.org/10.1080/13813455.2019.1680697
7. Mixo Baloyi, Ntethelelo Sibiya, Andile Khathi, Phikelelani Ngubane (2019) The Haematological Effects of Oleanolic Acid in Streptozotocin-Induced Diabetic Rats: Effects on Selected Markers. Journal of Diabetes Research https://doi.org/10.1155/2019/6753541
8. Asiphaphola Ludidi, Mixo Baloyi, Ntethelelo Sibiya, Andile Khathi, Phikelelani Ngubane (2019). The Effects of Momordica balsamina Methanolic Extract on Haematological Function in Streptozotocin-induced Diabetic Rats: Effects on Selected Markers. Biomedicine and Pharmacotherapy
9. Samkelisiwe Sibiya, Bonisiwe Msibi, Ntethelelo Sibiya, Andile Khathi, Phikelelani Ngubane (2019). The effect dioxidovanadium complex (v) on hepatic function in streptozotocin-induced diabetic rats. Canadian Journal of Physiology and Pharmacology https://doi.org/10.1139/cjpp-2019-0369
10. N Sibiya, M Mabandla (2018). The application of pectin-insulin patch prevents the onset of peripheral neuropathy-like symptoms in streptozotocin-induced diabetic rats. J Canadian Pharmacology and Physiology, doi: 10.1139/cjpp-2018-0415
11. N Sibiya, P Ngubane and M Mabandla (2017). The ameliorative effect of pectin-insulin patch on renal injury in streptozotocin-induced diabetic rats. Kidney and Blood Pressure https://doi.org/10.1159/000480395
12. N Sibiya, S Ngubane, M Mabandla (2017). Cardio-protective effects of pectin-insulin patch in streptozotocin-induced diabetic rats. Journal of Diabetes https://doi.org/10.1111/1753-0407.12538

Peer-reviewed conference proceedings:

Akinnuga, A.M., Siboto, A., Khumalo, B., Sibiya, N.H., Ngubane, P., & Khathi, A. Evaluation of the effects of bredemolic acid on selected markers of glucose homeostasis in diet-induced prediabetic rats.

47^th Conference of the Physiological Society of Southern Africa (PSSA), 18^th– 21^st August 2019, East London, South Africa.

Ntethelelo Sibiya, Metse Serumula and Cephas Musabayane (2014). Evaluation of the effects of oxidovanadium 2-pyridylbenzimidazole (Hpybz) compounds on glucose metabolism in liver and skeletal muscle cell lines

Physiological Society. 1 July 2014. University of Oxford. United Kingdom

Ntethelelo Sibiya, Metse Serumula, Rene Myburg & Cephas T Musabayane (2013). Antioxidant effects of oleanolic acid in livers, hearts and kidneys of streptozotocin-induced diabetic rats

41^st Conference of the Physiological Society of Southern Africa. 15-18 September 2013. University of the Limpopo (Medunsa campus). South Africa

Ntethelelo Sibiya, Metse Serumula, Rene Myburg & Cephas T Musabayane (2013). The effects of Syzygium aromaticum-derived-oleanolic acid (OA) on reactive oxygen species in the heart, liver and kidneys of STZ-induced diabetic rat

The Annual Society for Endocrinology conference. 19-22 March 2013. Harrogate International. United Kingdom

Recent former students:

1. C Baloyi (2020) M Med Sci (Summa Cum Laude): Effects of oleanolic acid on hematological changes and platelet induced endothelial dysfunction in streptozotocin-induced diabetes rats: Effect on selected markers
2. N Xulu (2020) MMed Sci: Effect of dioxidovanadium complex on haematological function and cardiac metabolism in streptozotocin-induced diabetic rats
3. B Khumalo (2020) MMedSci: Effect of Marmodica Balsamina on glucose handling in high fat high carbohydrate induced prediabetic model and glucose handling in C2C12 induced insulin resistant cell line: Effect on selected metabolic markers.
4. Palesa Molisi (2020) MMed Sci: An investigation of the association between diet-induced prediabetes and hypothalamic pituitary-adrenal axis activity in male Sprague Dawley rats
5. B Mkhize (2020) MMed Sci (Summa Cum Laude): An investigation on the activity of the renin-angiotensin-aldosterone system in selected organs of diet-induced pre-diabetes rats; Implications on progression towards type 2 diabetes.
6. A Siboto (2020) MMed Sci: An in vivo and in vitro analysis of ameliorative effects of a novel rhenium (V) compound with uracil derived ligand in a state of impaired glucose homeostasis
7. M Akinnuga (2020) PhD in Human Physiology: Investigating the effects of bredemolic acid on selected markers of some prediabetes-associated complications

Web Presence:

https://www.researchgate.net/profile/Ntethelelo_Sibiya

Awards and Grants:

NRF Black Academic Advancement Programme

NRF Thuthuka