Bruker Compact Liquid Chromatography Mass Spectrometry (LC-MS/MS)

By Dr Xavier Siwe Noundou

In June 2017, Rhodes University purchased a last generation of Quadrupole Time-of-Flight (Q-TOF) Mass Spectrometry system (Bruker Compact) through an NRF Grant Infrastructure Funding Instruments (NEP), secured by Prof Rui Krause.

This tandem (MS-MS) mass spectrometer can be used for structural and sequencing studies as well as qualitative and quantitative applications.

Some applications of this instrument include: determination of the purity of samples, sample confirmation, chemical modification, analysis of proteins, peptides, oligonucleotides, drug discovery, combinatorial chemistry, drug testing, water quality, food contamination, enzyme reaction, protein digestion, amino acids sequencing etc.

I would say that at Rhodes University, we are privileged enough to have this State-of-the-Art LC-MS/MS system and this would certainly improve learning at Rhodes University and speed up number of research projects, therefore increase the outputs for researchers working with the techniques associated to the instrument.